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ASPARTIC PROTEASES FOR COSMETIC USE

[Category : - Beauty, clothes & personal articles]
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The invention relates to aspartic proteases, and particularly to aspartic proteases for plants. Disclosed are modified plant aspartic proteases, and methods for their manufacture, and uses thereof. Particularly contemplated are the uses of aspartic proteases in inducing skin desquamation.rnrnOur client's researchers have discovered that the plant aspartic protease cardosin B shows skin desquamation activity without affecting cellular viability. These plant aspartic proteases have an enhanced ability to induce skin desquamation compared with mammalian aspartic proteases such as cathepsin D and other plant-derived proteases. rnrnA patent portfolio (US, EU, CA) is in place that protects the topical use of plant aspartic proteases for a range of applications, including use as an ingredient in cosmetics to improve the appearance of the skin or use in medical treatments to alleviate skin conditions such as xerosis, eczema, psoriasis or ichthyosis.rn rnThis patent portfolio will be of interest to companies operating in the personal care, cosmetics manufacturing and pharmaceutical market segments.rn

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US 9890372

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2biopatents (United Kingdom)

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